2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) affects the thyroid morphologically and/or functionally in adult animals. Recently, the National Toxicology Program conducted a 2-year gavage study of TCDD in female Harlan Sprague–Dawley rats. The only treatment-related alterations found in thyroid follicles were decreased luminal size and increased height of the follicular epithelial cells, without prominent protrusion into the lumen.
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The sectional epithelial height (SEH) of follicles in thyroids of
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Cystinosis induces follicle-autonomous thyrocyte proliferation and
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Low dose exposure to HBCD, CB-153 or TCDD induces
Astragaloside IV ameliorates pulmonary vascular remodeling in hypoxia- induced pulmonary hypertension by restraining the T follicular helper cell response and expanding T follicular regulatory cell response - ScienceDirect
Liver Enlargement - Hepatic Enzyme Induction: Histopathology