“Think about a brake when driving a car,” Chen explains. “If the brake is always engaged, you can’t drive. We found an siRNA that could remove the brake in this genetic pathway.”
Hearing Health Foundation (HHF) is the largest non-profit funder of hearing research. Since 1958, HHF has given away millions of dollars to hearing and balance research, including work that led to cochlear implant technology and now through the Hearing Restoration Project is working on a cure for hearing loss and tinnitus. HHF also publishes Hearing Health magazine, a free consumer resource on hearing loss and related technology, research, and products.
Drug-Like Cocktail Used by Researchers to Regenerate Hair Cells
Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate
Examples of stem-cell–derived hair-cell–like cells. (A) Strategy
Brain Sciences, Free Full-Text
Audiology Research, Free Full-Text
Frontiers Molecular and Clinical Significance of Fibroblast
Expansion and Differentiation of Progenitor Cells from Adult Mouse
Scientists use drug-like cocktail to regenerate hair cells in
Frontiers An in vivo Biomarker to Characterize Ototoxic
Inner Ear Organoids: Recent Progress and Potential Applications
Generation of inner ear hair cells by direct lineage conversion of
Reprogramming the Inner Ear to Regrow Hair Cells Shows Promise to
IJMS, Free Full-Text
Pharmaceuticals, Free Full-Text