Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 involving scientists from CNRS, ENS-PSL and supported by Inserm has demonstrated and described this phenomenon. Better understanding of mutations opens up prospects in the fight against resistance to antibiotics and anti-cancer therapies. This study was published in PNAS on 5 April 2021.
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DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis - ScienceDirect
24.2: DNA Mutations, Damage, and Repair - Biology LibreTexts
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Protein MutS - an overview
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From DNA Mutations to Protein Structure – Connected Biology
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Nonsense Mutation - an overview
Predicting the mutations generated by repair of Cas9-induced double-strand breaks